hrp0084p2-359 | Fat | ESPE2015

FTO rs9939609 Polymorphism is Associated with the Presence of Obstructive Sleep Apnoea in Obese Youth

Kao Kung-Ting , Alexander Erin , Harcourt Brooke E , Saffery Richard , Wake Melissa , McCallum Zoe , Werther George , Sabin Matthew

Background: Emerging evidence suggests FTO polymorphisms are associated with obesity-related comorbidities including type 2 diabetes (T2DM), hypertension and polycystic ovarian syndrome (PCOS). However association of FTO with other comorbidities such as obstructive sleep apnoea (OSA) in paediatric populations is less clear.Objective and hypotheses: To investigate the prevalence of obesity-related comorbidities according to FTO genotype in an obese paedia...